Clinical study

Tested where it counts: a clinical study on Streamcheck.

Streamcheck wasn't just built — it was clinically studied by urologists at German university hospitals, evaluated against scientific criteria and published in the specialist journal “Die Urologie”. The results show how precise at-home urological self-measurement can be.

Peer-reviewedJournal “Die Urologie”3 German university hospitals

Results

The results in numbers

These figures come directly from the study. They show how accurately Streamcheck measured under controlled conditions.

100 %

Clinically plausible flow curves

Rated by experienced urologists — with no relevant artifacts.

98.7 %

Overall accuracy of the biomarker analysis

Clearly above the pre-defined threshold of 90%.

0.99

Agreement of the pH measurement

Pearson correlation with the lab reference.

The study was a clinical feasibility study; the results refer to the conditions examined there.

Why it matters

Why a study makes the difference

An at-home measuring device is only as good as the reliability of its readings. It isn't enough for a system to be usable — it has to show that its measurements hold up to clinical scrutiny.

That is exactly what happened with Streamcheck. A clinical feasibility study examined whether key urological readings can be captured reliably in the home environment — carried out by experienced urologists and scientists from renowned German hospitals.

  • Department of Urology, Leipzig University Hospital

  • Department of Urology, Urologic Oncology and Robot-assisted Surgery, Gronau

  • Department of Urology and Pediatric Urology, Saarland University Hospital, Homburg

Published in “Die Urologie”

After scientific peer review, the results were published in the official journal of the German Society of Urology (DGU). Conducted under clinical conditions, independently assessed and published in a recognized specialist journal: that is the difference between a claim and evidence.

Study design

How the study was set up

A broad age range instead of a hand-picked ideal group — which makes the results more robust.

92

Participants enrolled

73

Data sets fully evaluated

23–89

Age range (years)

The study examined whether, at home, Streamcheck:

  • records flow curves reliably
  • determines urine volumes correctly
  • detects biomarkers precisely
  • is easy to use
  • is accepted by its users

The study was conducted following ethics committee approval — the procedure and the protection of participants were independently reviewed beforehand.

100 %

of the recorded flow curves were rated clinically plausible.

Urine flow

100 percent clinically plausible flow curves

Uroflowmetry — the measurement of urine flow — is considered one of the most important examinations for lower urinary tract symptoms under the guidelines of the urological societies EAU, ICI and AUA. In everyday practice it is nonetheless rarely performed, given the time and staff it requires.

In the study, participants performed this measurement themselves, at home. The recorded curves were then assessed by experienced urologists. The result: 100 percent of all measured flow curves were rated clinically plausible — with no relevant artifacts or irregularities. An examination that usually happens in the practice delivered, at home, a quality experienced urologists rated clinically plausible.

Biomarkers

High accuracy in the biomarker analysis

Alongside urine flow, Streamcheck analyzes selected urinary biomarkers. Here, too, the system reached very high values.

100 %

Sensitivity

Abnormal values were detected reliably.

> 95 %

Specificity

Normal values were reliably classified as such.

100 %

Negative predictive value

No abnormal case was missed.

The study authors particularly highlight sensitivity, specificity and the negative predictive value as markers of the system's reliability.

pH readings close to the lab reference too

For the pH measurement, Streamcheck showed excellent agreement with the reference readings: the Pearson correlation coefficient was 0.99 — practically matching the lab measurement.

Acceptance

High user satisfaction

Precision is of little use if a system isn't adopted in everyday life. That is why user acceptance was examined as well.

4.04 / 5

Average satisfaction on a scale from 1 to 5.

79.2%

Share who rated Streamcheck “satisfied” or “very satisfied”.

“The high participant satisfaction points to good acceptance among users.”

From the study, “Die Urologie”, 2026

The system

What Streamcheck measures

Streamcheck combines several established methods of basic urological diagnostics in one system for home use.

Uroflowmetry

Measurement of urine flow.

IPSS questionnaire

The International Prostate Symptom Score captures lower urinary tract symptoms in a structured way.

Biomarker analysis

Evaluation of relevant urinary values.

Digital trend tracking

Your readings as a trend in the app.

Automated evaluation

Rule-based recommendations from your readings.

Medical report

A structured report for your treating specialist.

The Streamcheck app evaluates your measurement data automatically and presents it clearly. When findings are abnormal, the automated evaluation recommends getting in touch with a physician or urologist. Repeatedly abnormal biomarkers — such as hematuria (blood in the urine) or proteinuria (protein in the urine) — lead to a recommendation for specialist assessment. The results are summarized in a structured medical report that you can make available to your doctor.

For you

What this means for you

The study proves two things that matter in everyday life.

Your readings hold up

What you measure at home reached, in the clinical evaluation, a quality a doctor can work with. You don't get a rough estimate, but reliable readings a doctor can interpret.

Have a basis earlier

In the authors' assessment, Streamcheck reaches men in particular who feel healthy but already have abnormal values — bringing them to medical assessment earlier. Those with normal readings can avoid unnecessary doctor visits. The biggest advantage lies in long-term measurement: single readings become a trend that reveals changes a snapshot would miss.

The authors' conclusion

What the study authors conclude

  • The clinical study confirms the performance, safety and usability of the Streamcheck system.
  • Streamcheck showed consistent and reliable measurement performance.
  • The combination of uroflow measurement and biomarker analysis is an innovative approach.
  • Long-term measurements open up new possibilities for health monitoring.
  • The system can make changes in voiding behavior (urination) and urine composition visible earlier.
“The SC confirms itself as a reliable measurement method for home use with high patient satisfaction. The SC thus represents a promising digital addition to urological care.”

Conclusion of the study authors (“SC” stands for Streamcheck), “Die Urologie”, 2026

Source

Peer-reviewed and clinically tested

The study results were published in the peer-reviewed journal “Die Urologie”. The study was conducted following ethics committee approval and included participants aged 23 to 89. The flow measurements were additionally assessed by experienced urologists, who rated 100 percent of the recorded curves clinically plausible.

Study

Wirth U., Holze S., Wagner C., Bonaventura A., Siemer S. “Validierung eines neuen portablen Messsystems für die diagnostische Heimnutzung — eine Machbarkeitsstudie.” Die Urologie, Springer Nature, 2026.

Authors

  • Ulrike Wirth & Sigrun Holze — Department of Urology, Leipzig University Hospital
  • Christian Wagner — Department of Urology, Urologic Oncology and Robot-assisted Surgery, Gronau
  • Alena Bonaventura & Stefan Siemer — Department of Urology and Pediatric Urology, Saarland University Hospital, Homburg
View the study on PubMed

Conducted at

Streamcheck does not replace a medical examination, diagnosis or treatment. If readings are abnormal or you have symptoms, always seek medical assessment. The study was a clinical feasibility study; the results refer to the conditions examined there.

Streamcheck Standard

Measure at home with an accuracy that has been clinically tested.

Streamcheck brings urological self-measurement into your routine — precise, discreet and ready to share with your doctor. The study shows what you can rely on.

Streamcheck Standard, a one-time 299 €.